Health Professionals looking for more information about Propax can find it here. See how Propax with NTFactor® can be an important part of the daily nutrition of your patients.

Health Professionals

Propax Research Highlights and Information for the Medical Community

Health Professionals
Clinical Pharmacology
Human Pharmacology
Propax Dosing

Propax w/ NTFactor® is a broad spectrum moderate dosed nutrient program clinically validated to reduce and eliminate fatigue 1,2,3. It contains a full spectrum of vitamins; both fat- and water-soluble, a full range of minerals; micro & macro, a complete group of anti-oxidants, pre- & pro-biotics, essential fatty acids along with the validated nutrient compound NTFactor® 1, 2, 3, 4, 5 which is also the tablet base and majority source of binder. The tablets are completely composed of food or food extracts and contains absolutely no non-nutritive material.

A unit dose is composed of four identical tablets and one soft gel capsule delivered in cellophane packets. The soft gel capsule contains Omega 3 fatty acids (EPA, DHA) while the remainder of the nutrients including NTFactor® are contained in the tablets.

Nutritional Benefits / Unique Mechanisms: The nutrient compound NTFactor® introduces ‘Membrane Lipid Replacement Technology’ and as such provides for the revitalization of cell and mitochondrial membrane including functions and integrity.6 Pre-clinical experiments demonstrate almost complete cessation of expected age-related loss of mitochondrial function, nerve function and accumulation of age-related genetic damage as test animals aged from the equivalent of early middle age to advanced age.1,2 Clinical trials demonstrate reversal of age-related loss of mitochondrial function in an elderly population to levels normal for young adults.1

Improved membrane fluidity and electrical potentials increase the utilization of the spectrum of nutrients present in Propax.

Moderate dosed and naturally complexed nutrients allow for effective adjunctive nutritional support with all current pharmaceuticals regimens including oncology.1, 2,3

Clinical Applications: In clinical trials Propax with NTFactor® reduced severe fatigue by 40% in 8 weeks.2 Double-blinded randomized trials demonstrate a majority of chemotherapy patients experience reduced fatigue, nausea, diarrhea, impaired taste, constipation, insomnia and other quality of life indicators when using Propax as an adjunct to chemotherapy.3

All chronic degenerative disease is accompanied or preceded by a reduction in mitochondrial function, a degradation of membrane lipids and loss of membrane fluidity.6 These are also characteristics of aging along with age-related damage to mitochondrial DNA. Furthermore, pharmaceutical regimens are typically toxic to mitochondria and accelerate membrane rancidity.6

Propax relives fatigue

Propax therefore should be a part of the daily regimen of all individuals concerned with quality of life preservation, disease prevention and mitigation as well as individuals interested in natural non-hormone anti-aging strategies6. It may also be used as an adjunct to any standard therapy.1, 2, 3

Dosing: Propax is available in unit doses of four tablets and one soft gel capsule per packet. Consumption of the tablets may be separated from consumption of the soft gel capsule by at least 30 minutes for optimal utilization. Tablets should also be consumed separately from any lecithin, choline, whey or essential fatty acid containing formulas or foods. These items may intefere with the absorption of NTFactor® . Since the inclusion of NTFactor® gives Propax tablets a complete food character the tablets may be taken away from food.

The number of packets administered daily is dependent on the individual’s experience of fatigue. Validated fatigue tools are available from NTI.

If the individual is chronically exposed to cyto-toxic chemicals the daily dose should be up to 3 packets per day.


For severe fatigue: 3 packets per day.

For moderate fatigue: 2 packets per day

For mild fatigue or general health purposes: 1 packet per day.

Note; based on clinical studies individuals experiencing moderate and severe fatigue will be able to reduce dosages to 1 packet per day within 12 weeks (P<0.0001)2.


1. Agadjanyan, M., Vasilevko, V., Ghochikyan, A., Berns, P., Kesslak, P., Settineri, R.A. and Nicolson, G.L. Nutritional supplement (NT Factor) restores mitochondrial function and reduces moderately severe fatigue in aged subjects. J. Chronic Fatigue Syndr. 2003; 11(3): 23-36.

2. Ellithorpe RR, Settineri R, Nicolson GL. Pilot Study: Reduction of fatigue by use of a dietary supplement containing glycophospholipids. JANA. 2003; 6(1):23-28.

3. Colodny L, Lynch K, Farber C, Papish S, et al. Results of a study to evaluate the use of Propax to reduce adverse effects of chemotherapy. JANA. 2000; 2:17-25

4. Seidman M, Khan MJ, Tang WX, Quirk WS. Influence of lecithin [NT Factor] on mitochondrial DNA and age-related hearing loss. Otolaryngol Head Neck Surg. 2002; 127:138-144.

5.Seidman M., Polyunsaturated Phosphatidylcholine in NTFactor® Improves Mitochondrial Function, Auditory Sensitivity and May Slow Some Aspects of the Aging Process Anti-Aging Medical News 2001; Winter: 5,16,32,44

6.Nicolson G.L., Lipid Replacement Therapy as an Adjunct for Chronic Fatigue, Anti-Aging and Restoration of Mitochondrial Function. JANA. 2003; 6(3):22-28

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© 2010 Nutritional Therapeutics, Inc. All Rights Reserved
These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any pharmaceutical product without first consulting your prescribing physician.